Aortic aneurysm and dissections are serious and sometimes life-threatening conditions that can be passed down between generations. Only 20% of affected patients have a known genetic cause for their aortic dissection and/or aneurysm. The aim of our study is to try to identify new genes that contribute to the development of these diseases, with the aim of discovering better and less invasive treatment options in a timely manner, improving survival and quality of life.