Understanding the Genetic Basis in a Thoracic Aortic Aneurysm and Dissection cohort using Next Generation Genetic Sequencing approach
Understanding the genetic cause of aortic aneurysm and dissection
Link to organisation:
Full description:
Aortic aneurysm and dissections are serious and sometimes life-threatening conditions that can be passed down between generations. Only 20% of affected patients have a known genetic cause for their aortic dissection and/or aneurysm. The aim of our study is to try to identify new genes that contribute to the development of these diseases, with the aim of discovering better and less invasive treatment options in a timely manner, improving survival and quality of life.
Opportunity Deadline
15th September 2025
Payment:
We will not be able to provide payment for the first meeting as this is pre-award. Payment for future meetings will be as per the NIHR guidelines.
Expenses:
Any reasonable expenses will be reimbursed for involvement post grant award (£5 reimbursement towards internet and computer access will be included)
Organisation
Sonalee Lab - The Marfan Trust
Since 2000, the Sonalee Lab has discovered new genes involved in ectopia lentis and inherited aortic disease. We have also conducted research that has influenced how disorders such as Marfan syndrome, are diagnosed and managed in the UK. https://www.marfantrust.org/pages/8-what-we-do
Details
Topic:
Stroke or cardiovascular disease
Location:
UK wide
Involvement type:
Disseminating
Reviewing
What support is offered?
N/A
Can the work be done from home?
Yes
Suitable for a beginner?
Yes
